In the second call of Valorisation Programme of NanoNextNL (December 2015) the following business case was awarded:
Surfix develops and provides innovative custom-made nanocoatings for micro- and nanotechnology and life sciences applications, based on chemical surface modification. With our proprietary technology local and material-selective surface modification can be achieved, improving the performance of complex devices such as microfluidic and lab-on-a-chip devices, diagnostic and biosensor chips, or microarrays.
At Surfix, we believe that local control of surface properties is essential for advanced micro- and nanotechnologies to be successful and revolutionize our world. Our team consists of highly motivated experts in the fields of organic, physical and biochemistry, enabling us to span a ‘chemical bridge’ between biology and physics. To this end we regularly join forces and via co-development provide custom-made solutions that facilitate our clients to achieve breakthrough innovations in their market.
Local surface modification
In the fields of PoC diagnostics, biosensing, and lab-on-a-chip positional control of the surface properties is of prime importance. Generally well-known multistep photolithographic and soft lithographic approaches are used to create micropatterns of functional nanocoatings, however, when more complex geometries are concerned, e.g. in microstructured or microfluidic devices, this is considerably more difficult. Via our proprietary surface modification technology even these complex devices can be locally functionalized with a molecular coating via a single step process. Local control of the surface properties will generate new opportunities in the development of reliable micro- and nanoscale devices.
Material-selective surface modification
For many applications material-selective surface modification will be beneficial. Surfaces that implement more than one material, such as most PoC diagnostic devices and biosensor chips significantly benefit from material-selective surface modification. The actual sensing element can be functionalized with nanocoatings readily available for bio-immobilization whereas biofouling moieties can be incorporated on the surrounding surface to prevent nonspecific binding interactions. In this manner material-selective surface modification enhances sensitivity and bioselectivity of such a device.